Chinese Journal of Organic Chemistry ›› 2020, Vol. 40 ›› Issue (6): 1461-1472.DOI: 10.6023/cjoc202001004 Previous Articles     Next Articles


尹彪, 付曼琳, 朱勍   

  1. 浙江工业大学生物工程学院 浙江省生物有机合成重点实验室 杭州 310014
  • 收稿日期:2020-01-02 修回日期:2020-03-10 发布日期:2020-03-31
  • 通讯作者: 朱勍
  • 基金资助:

Recent Advances in Transition Metal-O Weak Coordinated C(sp2)—H Direct Alkenylation Reaction

Yin Biao, Fu Manlin, Zhu Qing   

  1. Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310014
  • Received:2020-01-02 Revised:2020-03-10 Published:2020-03-31
  • Supported by:
    Project supported by the Natural Science Foundation of Zhejiang Province (No. LY17B060009).

Over the past decade, the C(sp2)-H functionalization has emerged as a powerful methodology due to its high efficiency, simplicity, and high atomic economy. Among them, weak coordination between transition metal and oxygen atom has become an important strategy for C(sp2)-H alkenylation of arenes. In this paper, the transition metal-catalyzed C(sp2)-H alkenylation of substrates containing hydroxy, aryl ether, aldehyde, carbonyl, carboxyl, amide, phosphoric acid and sulfonic acid and their derivatives groups is reviewed, and its future development trends are prospected.

Key words: C(sp2)-H functionalization, transition metal, alkenylation, weak coordination