Chinese Journal of Organic Chemistry ›› 2021, Vol. 41 ›› Issue (2): 695-701.DOI: 10.6023/cjoc202008012 Previous Articles     Next Articles



韩博士a, 时郑a, 何慧红a,*(), 张兴华a,b,*()   

  1. a 上海应用技术大学化学与环境工程学院 上海 201418
    b 宁波大学新药技术研究院 浙江宁波 315211
  • 收稿日期:2020-08-10 修回日期:2020-09-17 发布日期:2020-10-15
  • 通讯作者: 何慧红, 张兴华
  • 作者简介:
    * Corresponding authors. E-mail: ;
  • 基金资助:

Study on the Copper-Catalyzed Selective Allylation of Aryl (or Alkyl) Halides

Boshi Hana, Zheng Shia, Huihong Hea,*(), Xinghua Zhanga,b,*()   

  1. a School of Chemical and Environmental Engineering, Shanghai Institute of Technology, Shanghai 201418
    b Institute of Drug Discovery Technology, Ningbo University, Ningbo, Zhejiang 315211
  • Received:2020-08-10 Revised:2020-09-17 Published:2020-10-15
  • Contact: Huihong He, Xinghua Zhang
  • Supported by:
    the National Natural Science Foundation of China(21871182)

A practical method for the Cu-catalyzed coupling of aryl (or alkyl) halides with allylic acetates was described. This procedure effectively avoids the use of preformed Grignard reagent and affords allyl products with high to excellent regio- selectivity under relatively mild condition.

Key words: Keywords copper-catalyzed, allylation, regioselectivity