Chinese Journal of Organic Chemistry ›› 2024, Vol. 44 ›› Issue (2): 438-447.DOI: 10.6023/cjoc202307006 Previous Articles     Next Articles



付雅彤a, 孙超凡a, 张丹a, 金成国a, 陆居有b,*()   

  1. a 宜宾学院材料与化学工程学部 四川宜宾 644000
    b 海南大学化学化工学院 海口 570228
  • 收稿日期:2023-07-10 修回日期:2023-09-14 发布日期:2023-10-23
  • 基金资助:
    国家自然科学基金(22161015); 海南省自然科学基金(221RC448)

Recent Progress in B—H Bond Functionalization of nido-Carboranes

Yatong Fua, Chaofan Suna, Dan Zhanga, Chengguo Jina, Juyou Lub()   

  1. a Materials and Chemical Engineering Department, Yibin University, Yibin, Sichuan 644000
    b School of Chemistry and Chemical Engineering, Hainan University, Haikou 570228
  • Received:2023-07-10 Revised:2023-09-14 Published:2023-10-23
  • Contact:
  • Supported by:
    National Natural Science Foundation of China(22161015); Hainan Provincial Natural Science Foundation of China(221RC448)

nido-Carboranes are versatile building blocks in medicine, materials science, and organometallic/coordination chemistry. Recently, direct B—H activation and functionalization of nido-carboranes have received much attention. Achieving regioselectivity in polyhedral cage B—H activation among ten chemically similar B—H vertices is a long-standing challenge in carborane chemistry. In this context, the activation of exo-cage B—H vertices on the open C2B3 pentagonal plane of nido-carboranes has been extensively studied. However, few direct activation reactions of B—H vertices that are located on the closed polyhedral sphere in nido-carborane have been reported. The recent progress on the regioselective B—H bond functionalization reaction of nido-carboranes is summarized. This topic is categorized into open plane exo-B—H activation and polyhedral sphere B—H activation.

Key words: carboranes, B—H bond activation, regioselectivity, functionalization, directing group