Application of Functional Group Migration Strategies in Photodriven Difunctionalization of Unsaturated Hydrocarbons

doi:10.6023/cjoc202408025

Abstract

Difunctionalization of unsaturated hydrocarbons is a pivotal synthetic strategy enabling the conversion of alkenes and alkynes into high value-added compounds. It allows for the introduction of two functional groups into the unsaturated bond in a single step, facilitating the efficient construction of complex molecular architectures, which has been widely utilized in materials chemistry, pharmaceutical and fine chemical synthesis. Recently, significant progress has been made via free radical-mediated difunctionalization due to the extensive application of photocatalysis. However, highly selective difunctionalization reactions still remains challenging. The research progress of selective difunctionalization of unsaturated hydrocarbons using a free radical addition/functional group migration strategy over the past decade is summarized, and synthetic strategies and key reaction steps are systematically elaborated.

Key words: Visible-light-driven, Unsaturated hydrocarbon, Functional group migration, Difunctionalization

Cite this article

He Chonglong, Zhou Youkang, Duan Xin-Hua, Liu Le. Application of Functional Group Migration Strategies in Photodriven Difunctionalization of Unsaturated Hydrocarbons[J]. Chinese Journal of Organic Chemistry, doi: 10.6023/cjoc202408025.

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