Chinese Journal of Organic Chemistry ›› 2023, Vol. 43 ›› Issue (6): 2040-2052.DOI: 10.6023/cjoc202210015 Previous Articles     Next Articles


马佳敏, 李姣兄, 孟千森, 曾祥华*()   

  1. 嘉兴学院生物与化学工程学院 浙江嘉兴 314001
  • 收稿日期:2022-10-17 修回日期:2022-12-19 发布日期:2023-01-05
  • 基金资助:

Advances on the Radical Sulfonation of Alkynes

Jiamin Ma, Jiaoxiong Li, Qiansen Meng, Xianghua Zeng*()   

  1. College of Biological, Chemical Sciences and Engineering, Jiaxing University, Jiaxing, Zhejiang 314001
  • Received:2022-10-17 Revised:2022-12-19 Published:2023-01-05
  • Contact: E-mail:
  • Supported by:
    National Natural Science Foundation of Zhejiang Province(LY17B030011)

With sodium sulfinates, sulfonyl hydrazides, sulfinic acids, sulfonyl chlorides, dimethyl sulfoxide (DMSO) or 1,4- diazabicyclo[2.2.2]octane-1,4-diium-1,4-disulfinate (DABSO) as the sulfonyl source, which is easily formation of sulfone radical mediated by photocatalysis, electrocatalysis, metal catalysis and oxidant systems. Direct sulfone radical initiated difunctionalization of alkynes provides an efficient pathway for the synthesis of highly functionalized vinyl sulfones. According to the construction of C—X bond, the progress of involved sulfonation method in recent years is reviewed, and the difficulties and future development of this strategy are prospected.

Key words: sulfone radical, alkyne, difunctionalization, radical addition