Green Synthesis of Sulfinamides: Mild Oxidative Transformation Using Selectfluor in Water

doi:10.6023/cjoc202505009

Abstract

A green and efficient strategy for the synthesis of sulfinamides via the oxidation of sulfenamides using Selectfluor in water has been developed. This mild protocol possesses a good substrate scope, tolerating various functional groups. Reactions proceed smoothly under additive-free conditions, affording the corresponding sulfinamides in moderate to good yields. A successful scale-up attempt highlights the scalability and practical potential of this method.

Key words: Sulfenamides, Sulfinamide, Water-mediate, Oxidation

Cite this article

Jiahong Chen, Jingjing Xu, Hanjing Deng, You Zi. Green Synthesis of Sulfinamides: Mild Oxidative Transformation Using Selectfluor in Water[J]. Chinese Journal of Organic Chemistry, doi: 10.6023/cjoc202505009.

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