Rhodium-catalyzed synthesis of acyloin derivatives from cyclopropenones

doi:10.6023/cjoc202507023

Abstract

Cyclopropenones have been extensively utilized in catalytic ring-opening and ring-expansion reactions for the synthesis of unsaturated carbonyl compounds. In this study, we have accomplished the first rhodium-catalyzed ring-opening reaction of aryl-/alkyl-substituted cyclopropenones, successfully affording acyloin derivatives. This transformation represents a novel reaction pattern involving cyclopropenones. The resulting acyloin products constitute important building blocks in organic synthesis and serve as fundamental structural frameworks in numerous natural products.

Key words: cyclopropenone, rhodium catalysis, acyloin, ring-opening reaction

Cite this article

Caiyi Ren, Wennan Dong, Jinggong Liu, Shuang Yang, Xinqiang Fang. Rhodium-catalyzed synthesis of acyloin derivatives from cyclopropenones[J]. Chinese Journal of Organic Chemistry, doi: 10.6023/cjoc202507023.

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