Chinese Journal of Organic Chemistry ›› 2024, Vol. 44 ›› Issue (1): 291-300.DOI: 10.6023/cjoc202306002 Previous Articles     Next Articles


铑(III)催化苯甲亚胺酸乙酯和CF3-亚胺氧锍叶立德C—H 活化/环化反应合成CF3-1H-苯并[de][1,8]萘吡啶

文思a,b, 丁宇浩b, 田青于b, 葛进b, 程国林b,*()   

  1. a 安康学院化学化工学院 陕西安康 725000
    b 华侨大学材料科学与工程学院 厦门市光电材料及其先进制造重点实验室 福建厦门 361021
  • 收稿日期:2023-06-01 修回日期:2023-07-26 发布日期:2023-08-22
  • 基金资助:
    国家自然科学基金(22071068); 及华侨大学分析测试中心资助项目.

Rhodium(III)-Catalyzed Synthesis of CF3-1H-benzo[de][1,8]naph-thyridines via C—H Activation/Annulation of Benzimidates and CF3-Imidoyl Sulfoxonium Ylides

Si Wena,b, Yuhao Dingb, Qingyu Tianb, Jin Geb, Guolin Chengb()   

  1. a College of Chemistry and Chemical Engineering, Ankang University, Ankang, Shaanxi 725000
    b Xiamen Key Laboratory of Optoelectronic Materials and Advanced Manufacturing, College of Materials Science and Engineering, Huaqiao University, Xiamen, Fujian 361021
  • Received:2023-06-01 Revised:2023-07-26 Published:2023-08-22
  • Contact: *E-mail:
  • Supported by:
    National Natural Science Foundation of China(22071068); Instrumental Analysis Center of Huaqiao University.

A rhodium-catalyzed C—H activation/annulation domino reaction of benzimidates and CF3-imidoyl sulfoxonium ylides has been achieved. This synthetic strategy has good functional groups tolerance and universality of substrates, and a series of trifluoromethyl-containing 1H-benzo[de][1,8]naphthyridines were synthesized in 22%~86% yields.

Key words: rhodium catalysis, benzimidate, trifluoromethyl, sulfoxonium ylide, benzo[de][1,8]naphthyridine