Chinese Journal of Organic Chemistry ›› 2023, Vol. 43 ›› Issue (8): 2905-2912.DOI: 10.6023/cjoc202302023 Previous Articles     Next Articles


张彦波, 孙萌*()   

  1. 西北大学化学与材料科学学院 合成与天然功能分子教育部重点实验室 西安 710127
  • 收稿日期:2023-02-23 修回日期:2023-03-23 发布日期:2023-04-13
  • 基金资助:

Rh(III)-Catalyzed C(7)—H Formylmethylation of Indoline with Vinylene Carbonate

Yanbo Zhang, Meng Sun()   

  1. Key Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education, College of Chemistry and Materials Science, Northwest University, Xi'an 710127
  • Received:2023-02-23 Revised:2023-03-23 Published:2023-04-13
  • Contact: *E-mail:
  • Supported by:
    The National Natural Science Foundation of China(21702160)

A Rh(III)-catalyzed synthesis of arylacetaldehydes via C—H formylmethylation with vinylene carbonate has been developed. The reaction proceeded smoothly to give C7-functionalized N-(2-pyrimidyl)-indolines in moderate to good yields. This protocol features simple system, excellent regioselectivity, and good functional group compatibility.

Key words: rhodium catalysis, formylmethylation, indoline, vinylene carbonate