Chin. J. Org. Chem. ›› 1992, Vol. 12 ›› Issue (3): 260-263. Previous Articles     Next Articles

Original Articles

5'-脱氧-5'-氟-5-氟尿核苷的合成和性质

曾福金;周瑾;陈耀全   

  1. 中国科学院上海有机化学研究所
  • 发布日期:1992-06-25

Synthesis and properties of 5'-deoxy-5'-fluoro-5-fluorouridine

ZENG FUJIN;ZHOU JIN;CHEN YAOQUAN   

  • Published:1992-06-25

The title compound (I; R = R1 = F) (II) was prepared in 4 steps starting from I (R = OH, R1 = F). The properties of II e.g., H1 NMR, the reaction rate of isopropylidenation and deisopropylidenation were investigated in comparison with uridine (I; R = OH, R1 = H).

Key words: INFLUENCE, FLUORINE, NUCLEOSIDE, NMR SPECTROMETRY, REACTION RATE, ORGANO FLUORINE COMPOUNDS

CLC Number: