Chinese Journal of Organic Chemistry ›› 2020, Vol. 40 ›› Issue (9): 2641-2657.DOI: 10.6023/cjoc202004005 Previous Articles     Next Articles


孔瑶蕾, 孙晓彤, 翁建全   

  1. 浙江工业大学化学工程学院 杭州 310014
  • 收稿日期:2020-04-02 修回日期:2020-05-13 发布日期:2020-06-13
  • 通讯作者: 翁建全
  • 基金资助:

Selectfluor as “Fluorine-Free” Functional Reagent Applied to Organic Synthesis under Transition Metal-Free Conditions

Kong Yaolei, Sun Xiaotong, Weng Jianquan   

  1. College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014
  • Received:2020-04-02 Revised:2020-05-13 Published:2020-06-13
  • Supported by:
    Project supported by the Natural Science Foundation of Zhejiang Province (No. LY17C140003).

Selectfluor, a commercial electrophilic fluorination reagent with superior performance, is widely used in fluorination reactions. In recent years, Selectfluor has also been widely applied as "fluorine-free" functional reagent in organic synthesis. Especially the application of Selectfluor/transition metals synergetic catalytic system has made great progress. However, this catalytic system has some disadvantages, such as the use of expensive transition metals and environmental unfriendliness. Therefore, more and more attention has been paid to the application of Selectfluor as "fluorine-free" functional reagent under transition metal-free conditions. In this paper, classified by the type of reactions, the research progress of Selectfluor as a "fluorine-free" functional reagent in organic synthesis under transition metal-free conditions is reviewed, and their future outlook is also discussed.

Key words: Selectfluor, “fluorine-free” functional reagent, transition metal-free, organic synthesis