Study on synthesis of some new derivatives of sulfanilamide containing tetracarbon ring of squaric acid

Abstract

It is well-known that most sulfanilamides are used for the treatment infective or other diseases, whereas function of tetracarbon ring of squaric acid which has special structure and property has been proved by a large number of related studies. We have successfully introduced structural unit of some sulfanilamide into the tetracarbon ring. 14 new derivatives of sulfanilamide were obtained and their structures were determined. It is expected that combining structural unit of sulfanilamide with tetracarbon ring might lead to new bioactive compounds.

Key words: STRUCTURE CHARACTERISTICS, AMIDES P, ORGANIC SYNTHESIS, CYCLOBUTENE P, SQUARIC ACID, ACYL GROUP, KETONE P, BIOLOGICAL ACTIVITY

CLC Number:

O621

Cite this article

LI JUCAI;ZHOU HAIBING;CHEN YIZHAO. Study on synthesis of some new derivatives of sulfanilamide containing tetracarbon ring of squaric acid[J]. Chin. J. Org. Chem., 1997, 17(6): 507-512.

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