Syntheses and antibacterial activity of 3, 6-diaryl-5,  6-dihydro-s- triazolo[3, 4-b][1, 3, 4] thiadiazole

Chin. J. Org. Chem. ›› 1999, Vol. 19 ›› Issue (3): 288-292. Previous Articles Next Articles

Original Articles

3, 6-二芳基-5, 6-二氢均三唑[3, 4-b][1, 3, 4]噻二唑的合成及生物活性

王忠义;尤田耙;尤凌峰

中国科学技术大学化学系.合肥(230026)

发布日期:1999-06-25

Syntheses and antibacterial activity of 3, 6-diaryl-5, 6-dihydro-s- triazolo[3, 4-b][1, 3, 4] thiadiazole

Wang Zhongyi;You Tianpa;You Lingfeng

Univ Sci & Technol China, Dept Chem.Hefei(230026)

Published:1999-06-25

Abstract

Fifteen new chiral 3, 6-diaryl-5, 6-dihydro-s-triazolo[3, 4-b][1, 3, 4] thiadiazoles have been synthesized by the Mannich reaction of 3- aryl-4-amino-5-mercapto-1, 2, 4-triazole with various aldehydes in the presence of catalytic amounts of L-(+)-tartaric acid. Some compounds were found to have moderatel antibacterial activities.

Key words: TARTARIC ACID, SYNTHESIS, NMR, DIARYL GROUP, DIHYDRO, THIADIAZOLE, ADDITION REACTION, TRIAZOLE, BIOLOGICAL ACTIVITY

CLC Number:

R914

Cite this article

Wang Zhongyi;You Tianpa;You Lingfeng. Syntheses and antibacterial activity of 3, 6-diaryl-5, 6-dihydro-s- triazolo[3, 4-b][1, 3, 4] thiadiazole[J]. Chin. J. Org. Chem., 1999, 19(3): 288-292.

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3, 6-二芳基-5, 6-二氢均三唑[3, 4-b][1, 3, 4]噻二唑的合成及生物活性

Syntheses and antibacterial activity of 3, 6-diaryl-5, 6-dihydro-s- triazolo[3, 4-b][1, 3, 4] thiadiazole

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Abstract

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3, 6-二芳基-5, 6-二氢均三唑[3, 4-b][1, 3, 4]噻二唑的合成 及生物活性

Syntheses and antibacterial activity of 3, 6-diaryl-5, 6-dihydro-s- triazolo[3, 4-b][1, 3, 4] thiadiazole

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments

3, 6-二芳基-5, 6-二氢均三唑[3, 4-b][1, 3, 4]噻二唑的合成及生物活性