Chinese Journal of Organic Chemistry ›› 2004, Vol. 24 ›› Issue (4): 366-373. Previous Articles     Next Articles

Friedländer缩合反应研究新进展

杨定乔*, 吕芬, 郭维   

  1. 华南师范大学化学系 广州 510631
  • 收稿日期:2003-04-25 修回日期:2003-07-07 接受日期:2003-09-02 发布日期:2022-09-19
  • 基金资助:
    广东省教育厅2001年高校自然科学(No. 0126)资助项目

Recent Progress on Friedländer Condensation Reaction

YANG, Ding-Qiao*, LÜ, Fen, GUO, Wei   

  1. Department of Chemistry, South China Normal University, Guangzhou 510631
  • Received:2003-04-25 Revised:2003-07-07 Accepted:2003-09-02 Published:2022-09-19
  • Contact: *E-mail: yangdq@scnu.edu.cn

The o-aminobenzaldehyde reacts with all kinds of α-H aldehydes and ketones by Friedländer condensation reaction, therefore Friedländer condensation reaction has been applied in many fields such as heterocyclic chemistry, natural product chemistry, pharmaceutical chemistry, coordinationchemistry, organometallic chemistry and asymmetric organic synthesis. The recentprogress of Friedländer condensation reaction is reviewed in this paper.

Key words: Friedländer condensation reaction, o-aminobenzaldehyde, quinoline derivative, heterocyclic chemistry, asymmetric synthesis, drug synthesis