Chin. J. Org. Chem. ›› 2005, Vol. 25 ›› Issue (01): 53-58. Previous Articles     Next Articles

Review

生物催化用于C—C键的立体选择性合成

李祖义*,陈颖   

  1. 中国科学院上海有机化学研究所 上海 200032
  • 收稿日期:2004-03-11 修回日期:2004-03-12 发布日期:2004-12-30
  • 通讯作者: 李祖义

Application of Biocatalysis in Stereoselective Formation of

LI Zu-Yi*,CHEN Ying   

  1. Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032
  • Received:2004-03-11 Revised:2004-03-12 Published:2004-12-30
  • Contact: LI, Zu-Yi

The stereoselective formation of C—C bonds is a central aspect of organic synthetic chemistry. The stereoselectivity of biocatalysts is one of their major advantages and has fueled widespread research on enzymes for C—C coupling. Recent publications on C—C coupling in biotransformation were summarized with special focus on the application of aldolases and ketolases in this review.

Key words: aldolase, biocatalysis, ketolase