Asymmetric Synthesis of Tailor-made α-Amino Acids by ChiralAuxiliaries: Glycine Equivalent Approach

Chin. J. Org. Chem. ›› 2005, Vol. 25 ›› Issue (08): 881-892. Previous Articles Next Articles

Review

手性辅基法不对称合成特殊结构α-氨基酸——甘氨酸等当体途径

李振江*，万红贵，韦萍，石玉瑚，欧阳平凯

(¹南京工业大学制药与生命科学学院南京210009)
(²新疆大学化学与化工学院乌鲁木齐830046)

收稿日期:2004-06-25 修回日期:2004-12-03 发布日期:2005-07-30
通讯作者: 李振江

Asymmetric Synthesis of Tailor-made α-Amino Acids by ChiralAuxiliaries: Glycine Equivalent Approach

LI Zhen-Jiang*,WAN Hong-Gui,WEI Ping,SHI Yu-Hu
OUYANG Ping-Kai

(¹College of Life Science and Pharmaceutical Engineering, Nanjing University of Tech-nology, Nanjing 210009)
(²College of Chemistry and Chemical Engineering, Xinji-ang University, Urumqi 830008)

Received:2004-06-25 Revised:2004-12-03 Published:2005-07-30
Contact: LI Zhen-Jiang

Abstract

Tailor-made α-amino acids have played an important role in current life science research and biomedical development. Among the methodologies of α-amino acid asymmetric synthesis, chiral auxiliary strategy received most intensive and extensive investigations. Recent development in this strategy was outlined. Detailed critical review on the glycine equivalent approach in the last ten years was given.

Key words: asymmetric synthesis, chiral auxiliary, glycine equivalent, α-amino acid

Cite this article

LI Zhen-Jiang*,WAN Hong-Gui,WEI Ping,SHI Yu-Hu
OUYANG Ping-Kai. Asymmetric Synthesis of Tailor-made α-Amino Acids by ChiralAuxiliaries: Glycine Equivalent Approach[J]. Chin. J. Org. Chem., 2005, 25(08): 881-892.

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手性辅基法不对称合成特殊结构α-氨基酸——甘氨酸等当体途径

Asymmetric Synthesis of Tailor-made α-Amino Acids by ChiralAuxiliaries: Glycine Equivalent Approach

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