Chin. J. Org. Chem. ›› 2006, Vol. 26 ›› Issue (9): 1279-1283. Previous Articles     Next Articles

Reports

S-2-甲氧基环己酮的合成研究

毛海舫,潘仙华*,郎希红   

  1. (上海应用技术学院 生物与食品工程系 上海 200235)
  • 收稿日期:2005-10-26 修回日期:2005-12-28 发布日期:2006-09-11
  • 通讯作者: 潘仙华

Synthetic Study on S-2-Methoxycyclohexanone

MAO Hai-Fang,PAN Xian-Hua*,LANG Xi-Hong   

  1. (School of Biotechnology and Food Processing Engineering, Shanghai Institute of Technology, Shanghai 200235)
  • Received:2005-10-26 Revised:2005-12-28 Published:2006-09-11
  • Contact: PAN Xian-Hua

The synthetic method for the production of S-2-methoxycyclohexanone has been improved. The synthetic process, featured with high yield and low cost, can be applicable to the industrial production. The key intermediate 2, used for the preparation of the new classical β-lactam of sanfetrinem cilexetil, was obtained from the S-2-methoxycyclohexanone.

Key words: sanfetrinem cilexetil, β-lactam, asymmetric synthesis, S-2-methoxycyclohexanone