A novel p-/n-alternating 3-dodecyloxythiophene-co-1，3，4-Oxadiazole was synthesized by Heck coupling method and characterized by 1H NMR and gel permeation chromatography (GPC). The electrochemical and optical properties were investigated using cyclic voltammetry，UV-vis spectroscopy and photoluminescence (PL). The UV-vis maxima absorption was at 314nm and PL emission maxima was at 401nm in CHCl3 solution and transmitted bright blue color with the weight average of 5287. The PL emission maxima is blue-shifted 115nm in comparing to the homopolymer (516nm) in solution. In the cyclic voltammetry measurements, 3-dodecyloxythiophene-co-1，3，4-oxadiazole copolymer shows reversible n- and p-doping processes. The electron affinity (Ea) value is at -2.88ev, which will facilitate the electron injection from cathode. The facts imply that this alternation 3-dodecyloxythiophene-co-1，3，4-oxadiazole copolymer might be promising polymer for high performance OLED materials with hole-electron recombination.

Key words: polythiophene, oxadiazole, copolymer, organic light emitting diodes (OLED)