One-Pot Preparation of Fluorinated 4(3H)-Quinazolinones under Microwave Irradiation and Solvent-Free Conditions

Chin. J. Org. Chem. ›› 2011, Vol. 31 ›› Issue (08): 1272-1276. Previous Articles Next Articles

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微波促进下无溶剂一锅法合成含氟喹唑啉-4(3H)-酮类化合物

商文丽，章建民*，金见安，陈晓蕾

(上海大学理学院化学系上海 200444)

收稿日期:2010-10-21 修回日期:2011-01-19 发布日期:2011-03-14
通讯作者: 章建民 E-mail:jmzhang@shu.edu.cn;

One-Pot Preparation of Fluorinated 4(3H)-Quinazolinones under Microwave Irradiation and Solvent-Free Conditions

SHANG Wen-Li, ZHANG Jian-Min, JIN Jian-An, CHEN Xiao-Lei

(Department of Chemistry, School of Science, Shanghai University, Shanghai 200444)

Received:2010-10-21 Revised:2011-01-19 Published:2011-03-14

A facile one-pot method has been developed for the synthesis of ?uorine-containing 4(3H)-quinazolinones by a three-component coupling of anthranilic acid, triethyl orthoformate and ?uorinated anilines under microwave irradiation and solvent-free conditions. All new compounds are fully characterized by spectral methods, especially, fluorescence.

Key words: fluorinated 4(3H)-quinazolinones, microwave, one-pot reaction, solvent free, fluorescence emission spectrum

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SHANG Wen-Li, ZHANG Jian-Min, JIN Jian-An, CHEN Xiao-Lei. One-Pot Preparation of Fluorinated 4(3H)-Quinazolinones under Microwave Irradiation and Solvent-Free Conditions[J]. Chin. J. Org. Chem., 2011, 31(08): 1272-1276.

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微波促进下无溶剂一锅法合成含氟喹唑啉-4(3H)-酮类化合物

One-Pot Preparation of Fluorinated 4(3H)-Quinazolinones under Microwave Irradiation and Solvent-Free Conditions

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