Synthesis of Chiral Molecular Tweezers Based on O,O'-Diphenic Acid under Microwave Irradiation

Chin. J. Org. Chem. ›› 2007, Vol. 27 ›› Issue (07): 898-901. Previous Articles Next Articles

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联苯二甲酸类手性分子钳的微波合成

石云，赵志刚*，刘兴利

(西南民族大学化学与环境保护工程学院成都 610041)

收稿日期:2007-01-21 修回日期:1900-01-01 发布日期:2007-06-30
通讯作者: 赵志刚*

Synthesis of Chiral Molecular Tweezers Based on O,O'-Diphenic Acid under Microwave Irradiation

SHI Yun,ZHAO Zhi-Gang*,LIU Xing-Li

(College of Chemistry and Environmental Protection Engineering, Southwest University for Nationalities, Chengdu 610041)

Received:2007-01-21 Revised:1900-01-01 Published:2007-06-30
Contact: ZHAO Zhi-Gang*

Abstract

Seven chiral molecular tweezers have been synthesized by using O,O'-diphenic acid as a spacer and L-amino acid methyl esters as arms under microwave irradiation. Their structures were confirmed by ¹H NMR, IR, MS spectra and elemental analysis. Compared with the conventional heating method, this method considerably increased the reaction rate and yield. The preliminary results indicate that these chiral molecular tweezers have good enantioselective recognition for D/L- amino acid methyl esters.

Key words: molecular recognition, chiral molecular tweezer, microwave irradiation, O,O'-diphenic acid

Cite this article

SHI Yun,ZHAO Zhi-Gang*,LIU Xing-Li. Synthesis of Chiral Molecular Tweezers Based on O,O'-Diphenic Acid under Microwave Irradiation[J]. Chin. J. Org. Chem., 2007, 27(07): 898-901.

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联苯二甲酸类手性分子钳的微波合成

Synthesis of Chiral Molecular Tweezers Based on O,O'-Diphenic Acid under Microwave Irradiation

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