Chin. J. Org. Chem. ›› 1986, Vol. 6 ›› Issue (4): 281-285. Previous Articles     Next Articles

5β,3α-羟基-7-羰基-胆烷酸的还原反应

庄治平;陈英;周维善   

  1. 中国科学院上海有机化学研究所
  • 发布日期:1986-08-25

Reduction of 5\b\,3\a\-hydroxy-7-keto-cholic acid

ZHUANG ZHIPING;CHEN YING;ZHOU WEISHAN   

  • Published:1986-08-25

Reduction of the title compound (I) with hydride reducing agents gave mainly 7a-hydroxy derivative, whereas reduction with Li or Na gave mainly 7b-hydroxy derivative The reaction mechanism is discussed.

Key words: CHOLANES, REACTION MECHANISM, DEOXYCHOLIC ACID, CARBONYL COMPOUNDS, REDUCTION REACTION, BILE ACID, FEL URSI

CLC Number: