Chin. J. Org. Chem. ›› 2005, Vol. 25 ›› Issue (02): 208-209. Previous Articles    

Reports

5-烃基丙二酸亚异丙酯的Mannich碱与甲基酮的缩合反应

李景华*,1,李祖光2   

  1. (1浙江工业大学药学院 杭州 310014)
    (2浙江工业大学化工与材料学院 杭州 310014)
  • 收稿日期:2004-05-10 修回日期:2004-09-01 发布日期:2005-01-15
  • 通讯作者: 李景华

Condensation of Mannich Base of Isopropylidene 5-Alkylmalonate with Methyl Ketones

LI Jing-Hua*,1,LI Zhu-Guang2   

  1. (1 College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014)
    (2 College of Chemical Engineering and Materials, Zhejiang University of Technol-ogy, Hangzhou 310014)
  • Received:2004-05-10 Revised:2004-09-01 Published:2005-01-15
  • Contact: LI Jing-Hua

Isopropylidene 5-(3-oxo-alkyl)malonates (3) were synthesized by condensation of Mannich base of isopropylidene malonate with methyl ketones in the presence of faint acid, such as acetic acid.

Key words: isopropylidene malonate, Mannich base, methyl ketone, condensation