Chin. J. Org. Chem. ›› 2008, Vol. 28 ›› Issue (03): 440-442. Previous Articles     Next Articles

Original Articles

微波辐射下4,6-二羟基嘧啶与醛的反应研究

唐自强*,a,徐佳宁b,屠树江*,b,陈艳a,姜波b,贾润红b   

  1. (a徐州工程学院化学化工学院 徐州 221006)
    (b徐州师范大学化学化工学院 徐州 221116)
  • 收稿日期:2007-01-19 修回日期:2007-08-25 发布日期:2008-03-18
  • 通讯作者: 唐自强

Reaction of Pyrimidine-4,6-diol with Aldehydes under Microwave Irradiation

TANG Zi-Qiang*,a,XU Jia-Ningb,TU Shu-Jiang*,b
CHEN Yana,JIANG Bob,JIA Run-Hongb   

  1. (a School of Chemistry and Chemical Engineering, Xuzhou Institute of Technology, Xuzhou 221006)
    (b School of Chemistry and Chemical Engineering, Xuzhou Normal Univer-sity, Xuzhou 221116)
  • Received:2007-01-19 Revised:2007-08-25 Published:2008-03-18
  • Contact: TANG Zi-Qiang

The reaction of double equivalent pyrimidine-4,6-diol with aldehydes afforded 6-hydroxy-5-[(4-hydroxy-6-oxo-1,6-dihydropyrimidin-5-yl)arymethyl]pyrimidin-4(3H)-one deriva-tives under microwave irradiation using methylamine as a catalyst and acetic acid as a solvent.

Key words: pyrimidine-4,6-diol, bipyrimidi, microwave irradiation