Chin. J. Org. Chem. ›› 2006, Vol. 26 ›› Issue (11): 1463-1467. Previous Articles     Next Articles

Review

脯氨酸催化不对称羟醛缩合反应机理研究进展

樊建芬*,a,孙云鹏a,肖鹤鸣b   

  1. (a苏州大学化学化工学院江苏省有机合成重点实验室 苏州 215123)
    (b南京理工大学化工学院 南京 210094)
  • 收稿日期:2005-07-18 修回日期:1900-01-01 发布日期:2006-10-27
  • 通讯作者: 樊建芬

Progress in the Study on the Reaction Mechanisms of Proline-Catalyzed Asymmetric Direct Aldol Reactions

FAN Jian-Fen*,a,SUN Yun-Penga,XIAO He-Mingb   

  1. (a Key Laboratory of Organic Synthesis of Jiangsu Province, Faculty of Chemistry and Chemical En-gineering,
    Suzhou University, Suzhou 215123)
    (b Faculty of Chemical Engi-neering, Nanjing University of Science and Technology, Nanjing 210094)
  • Received:2005-07-18 Revised:1900-01-01 Published:2006-10-27
  • Contact: FAN Jian-Fen

Asymmetric direct aldol reaction is one of the central study issues in the field of asymmetric synthesis. In this review, reaction mechanisms of proline-catalyzed intra- and inter-molecular asymmetric aldol reactions are presented and discussed.

Key words: asymmetric direct aldol reaction, reaction mechanism, proline