Knoevenagel Condensation Reaction Catalyzed with Ionic Liquid Functionalized SiO2

Chin. J. Org. Chem. ›› 2007, Vol. 27 ›› Issue (04): 483-487. Previous Articles Next Articles

Original Articles

离子液体功能化二氧化硅催化Knoevenagel反应

厉嘉云，彭家建，邱化玉，蒋剑雄，邬继荣
倪勇，来国桥*

(杭州师范学院有机硅化学及材料技术教育部重点实验室杭州 310012)

收稿日期:2006-06-23 修回日期:1900-01-01 发布日期:2007-03-29
通讯作者: 来国桥

Knoevenagel Condensation Reaction Catalyzed with Ionic Liquid Functionalized SiO₂

LI Jia-Yun, PENG Jia-Jian, QIU Hua-Yu, JIANG Jian-Xiong, WU Ji-Rong
NI Yong, LAI Guo-Qiao*

(Key Laboratory of Organosilicon Chemistry and Material Technology of Ministry of Education, Hangzhou Teachers College,
Hangzhou 310012)

Received:2006-06-23 Revised:1900-01-01 Published:2007-03-29
Contact: LAI Guo-Qiao

Abstract

The Knoevenagel condensation of a series of aromatic aldehydes with active methylene compounds proceeded smoothly in the presence of catalytic amounts of ionic liquid functionalized SiO₂ at 100 ℃ without any additional volatile organic solvents, and the desired alkenes were obtained in good purity with excellent yields. In particular, when the Knoevenagel condensation of 2-hydroxybenzaldehyde was conducted with ethyl 2-cyanoacetate, 3-ethoxycarbonylcoumarin was obtained by simultaneous cyclization and alcoholysis of cyanide. In addition, the catalyst can be used recyclably.

Key words: Knoevenagel condensation, functionalized SiO₂, ionic liquid

Cite this article

LI Jia-Yun, PENG Jia-Jian, QIU Hua-Yu, JIANG Jian-Xiong, WU Ji-Rong
NI Yong, LAI Guo-Qiao*. Knoevenagel Condensation Reaction Catalyzed with Ionic Liquid Functionalized SiO_{2[J]. Chin. J. Org. Chem., 2007, 27(04): 483-487.}

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离子液体功能化二氧化硅催化Knoevenagel反应

Knoevenagel Condensation Reaction Catalyzed with Ionic Liquid Functionalized SiO₂

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