Chin. J. Org. Chem. ›› 2008, Vol. 28 ›› Issue (9): 1501-1514.     Next Articles

Review

具有生理活性的含氧、氮、硫杂原子螺环化合物的研究进展

魏荣宝* ; 刘 博; 刘 洋; 郭金晶; 张大为   

  1. 天津理工大学化学化工学院 天津 300191
  • 收稿日期:2007-06-30 修回日期:2008-12-06 发布日期:2008-09-20
  • 通讯作者: 魏荣宝

Progress in the Studies on Biological Activities of O, N or S-Containing Spiro Compounds

WEI, Rong-Bao* ; LIU, Bo; LIU, Yang; GUO, Jin-Jing; ZHANG, Da-Wei   

  1. College of Chemistry & Chemical Engineering, Tianjin University of Technology, Tianjin 300191)
  • Received:2007-06-30 Revised:2008-12-06 Published:2008-09-20
  • Contact: wrb_111@126.com

The recent progress in the studies on biological activities of O, N or S-containing spiro compounds is reviewed. The spiro compounds of structural feature and biological activities are described in detail and the synthetic methods of some spiro organic compounds are also provided. At last the prospects of this kind of spiro compounds are made.

Key words: spiro-compound, pharmaceutical, chiral axis, biological activity