Reformatsky Reaction Promoted by [bmim]Cl-CrCl2 Ionic Liquid

Chin. J. Org. Chem. ›› 2009, Vol. 29 ›› Issue (10): 1650-1653. Previous Articles Next Articles

Notes

离子液体[bmim]Cl-CrCl2促进的Reformatsky反应研究

刘长春* 袁加程谭佩毅金德宽

(江苏食品职业技术学院生物化工系淮安 223003)

收稿日期:2009-02-20 修回日期:2009-04-21 发布日期:2009-05-25

Reformatsky Reaction Promoted by [bmim]Cl-CrCl2 Ionic Liquid

Liu, Changchun* Yuan, Jiacheng Tan, Peiyi Jin, Dekuan

(Department of Biochemical Engineering, Jiangsu Food Science College, Huai'an 223003)

Received:2009-02-20 Revised:2009-04-21 Published:2009-05-25

Abstract

Ionic liquid [bmim]Cl-CrCl2 was synthesized from anhydrous chromium(II) chloride and 1-butyl-3-methylimidazolium chloride ([bmim]Cl). The effects of the molar ratio of CrCl2 to [bmim]Cl, ionic liquid to substrates and various substrates on Reformatsky reaction were investigated. β-Hydroxy es-ters and β-hydroxy ketones were obtained by the reactions of α-bromoesters or α-bromoacetophenone with aldehydes or ketones under mild conditions in excellent yields in the presence of [bmim]Cl-CrCl2. The ionic liquid could be reused.

Key words: [bmim]Cl-CrCl2, Reformatsky reaction, ionic liquid, β-hydroxy ester, β-hydroxy ketone

Cite this article

LIU Chang-Chun, YUAN Jia-Cheng, TAN Pei-Yi, JIN De-Kuan. Reformatsky Reaction Promoted by [bmim]Cl-CrCl2 Ionic Liquid[J]. Chin. J. Org. Chem., 2009, 29(10): 1650-1653.

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离子液体[bmim]Cl-CrCl2促进的Reformatsky反应研究

Reformatsky Reaction Promoted by [bmim]Cl-CrCl2 Ionic Liquid

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