Solvent-Free Achiral Cyanosilylation of Aldehydes and Ketones Catalyzed by LiNTf2

doi:10.6023/cjoc1110242

Chin. J. Org. Chem. ›› 2012, Vol. 32 ›› Issue (05): 934-938.DOI: 10.6023/cjoc1110242 Previous Articles Next Articles

Notes

无溶剂条件下LiNTf₂ 催化的醛和酮的非手性硅氰化反应研究

王宏社, 曾君娥

宝鸡文理学院化学化工系陕西省植物化学重点实验室宝鸡 721013

收稿日期:2011-10-24 修回日期:2011-12-20 发布日期:2012-01-11
通讯作者: 王宏社 E-mail:hongshewang@126.com
基金资助:
陕西省教育厅科研计划(No. 09JK332)和宝鸡文理学院重点(No. ZK1053)资助项目.

Solvent-Free Achiral Cyanosilylation of Aldehydes and Ketones Catalyzed by LiNTf₂

Wang Hongshe, Zeng June

Shaanxi Key Laboratory for Phytochemistry, Department of Chemistry and Chemical Engineering, Baoji University of Arts and Sciences, Baoji 721013

Received:2011-10-24 Revised:2011-12-20 Published:2012-01-11
Supported by:
Project supported by the Scientific Research Program of Shaanxi Provincial Education Deparment (No. 09JK332) and the Key Project of Baoji University of Arts and Sciences (No. ZK1053).

An efficient method for the addition of trimethylsilyl cyanide (TMSCN) to various aldehydes and ketones has been described using LiNTf₂ (1 mol%) as a catalyst at room temperature under solvent-free conditions. The advantages of this method are easy work-up, mild reaction conditions, high yields and the catalyst exhibited remarkable reusable activity.

Key words: LiNTf₂, aldehyde, ketone, cyanosilylation, solvent-free

Cite this article

Wang Hongshe, Zeng June. Solvent-Free Achiral Cyanosilylation of Aldehydes and Ketones Catalyzed by LiNTf₂[J]. Chin. J. Org. Chem., 2012, 32(05): 934-938.

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无溶剂条件下LiNTf₂ 催化的醛和酮的非手性硅氰化反应研究

Solvent-Free Achiral Cyanosilylation of Aldehydes and Ketones Catalyzed by LiNTf₂

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无溶剂条件下LiNTf2 催化的醛和酮的非手性硅氰化反应研究