Facile Synthesis of Ferrocenylchalcone Promoted by Ionic Liquid or Phase-Transfer Catalyst

doi:10.6023/cjoc201511045

Chin. J. Org. Chem. ›› 2016, Vol. 36 ›› Issue (5): 1118-1121.DOI: 10.6023/cjoc201511045 Previous Articles Next Articles

NOTE

离子液体/相转移催化剂促进的二茂铁基查尔酮的合成

赵海英, 尹凤楠, 于玲岩, 李保国, 边占喜

内蒙古大学化学化工学院内蒙古自治区精细有机合成重点实验室呼和浩特 010021

收稿日期:2015-11-25 修回日期:2015-12-14 发布日期:2016-01-15
通讯作者: 赵海英, 边占喜 E-mail:hyzhao@imu.edu.cn;bzx1957@sina.com
基金资助:
国家自然科学基金(No. 21562032)、内蒙古自治区高等学校科学研究(No. NJZZ001)和内蒙古自治区自然科学基金(Nos. 2013MS0207, 2014JQ02)资助项目.

Facile Synthesis of Ferrocenylchalcone Promoted by Ionic Liquid or Phase-Transfer Catalyst

Zhao Haiying, Yin Fengnan, Yu Lingyan, Li Baoguo, Bian Zhanxi

Inner Mongolia Key Laboratory of Fine Organic Synthesis, College of Chemistry and Chemical Engineering, Inner Mongolia University, Hohhot 010021

Received:2015-11-25 Revised:2015-12-14 Published:2016-01-15
Supported by:
Project supported by the National Natural Science Foundation of China (No. 21562032), the Research Program of Science and Technology at Universities of Inner Mongolia (No. NJZZ001) and the Natural Science Foundation of Inner Mongolia (Nos. 2013MS0207, 2014JQ02).

1. Facile Synthesis of Ferrocenylchalcone Promoted by Ionic Liquid or Phase-Transfer Catalyst.PDF(2144KB)

Abstract

The Claisen-Schmidt condensation of acetylferrocene with arylaldehydes in the presence of ionic liquids (ILs) or phase-transfer catalysts (PTCs) provided the corresponding ferrocenylchalcones in high yields, and PTCs can promote the condensation reaction better than those of ILs. Optimum conditions were as follows: molar ratio of acetylferrocene, arylaldehyde, n-Bu₄NPF₆ and NaOH is 1:1:2.5:0.75, and the appropriate reaction temperature is 35 ℃ in anhydrous EtOH.

Key words: ferrocene, chalcone, ionic liquid, phase-transfer catalyst, Claisen-Schmidt condensation

Cite this article

Zhao Haiying, Yin Fengnan, Yu Lingyan, Li Baoguo, Bian Zhanxi. Facile Synthesis of Ferrocenylchalcone Promoted by Ionic Liquid or Phase-Transfer Catalyst[J]. Chin. J. Org. Chem., 2016, 36(5): 1118-1121.

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离子液体/相转移催化剂促进的二茂铁基查尔酮的合成

Facile Synthesis of Ferrocenylchalcone Promoted by Ionic Liquid or Phase-Transfer Catalyst

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