Copper-Promoted Direct Nitration of Arenes Assisted by an N,O-Bidentate Directing System

doi:10.6023/cjoc201901015

Chin. J. Org. Chem. ›› 2019, Vol. 39 ›› Issue (6): 1761-1766.DOI: 10.6023/cjoc201901015 Previous Articles Next Articles

Special Issue: 金属有机化学；碳氢活化合辑2018-2019

Articles

N,O-双齿螯合作用下铜促进的C-H键直接硝基化反应

王云龙^a, 张林宝^b, 牛俊龙^a, 宋毛平^a

a 郑州大学化学与分子工程学院郑州 450001;
b 青岛科技大学化学与分子工程学院青岛 266042

收稿日期:2019-01-11 修回日期:2019-02-25 发布日期:2019-03-08
通讯作者: 牛俊龙, 宋毛平 E-mail:niujunlong@zzu.edu.cn;mpsong@zzu.edu.cn
基金资助:
国家自然科学基金（Nos.21772179，21672192）和河南省高校科技创新人才计划（No.19HASTIT038）资助项目.

Copper-Promoted Direct Nitration of Arenes Assisted by an N,O-Bidentate Directing System

Wang Yunlong^a, Zhang Linbao^b, Niu Junlong^a, Song Maoping^a

a College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001;
b College of Chemistry and Molecular Engineering, Qingdao University of Science & Technology, Qingdao 266042

Received:2019-01-11 Revised:2019-02-25 Published:2019-03-08
Contact: 10.6023/cjoc201901015 E-mail:niujunlong@zzu.edu.cn;mpsong@zzu.edu.cn
Supported by:
Project supported by the National Natural Science Foundation of China (Nos. 21772179, 21672192), the Program for Science & Technology Innovation Talents in Universities of Henan Province (No. 19HASTIT038).

1. Copper-Promoted Direct Nitration of Arenes Assisted by an N,O-Bidentate Directing System.PDF(9940KB)

Abstract

Cu(Ⅱ)-promoted C-H nitration of arenes has been disclosed with the aid of N,O-bidentate directing group. The protocol was operationally simple by using NaNO₂as the nitration source. Various amide substrates were tolerated in the reaction system, which establishes opportunities for developing simple and facile methods, and enriches the strategies to access aromatic nitro derivatives.

Key words: C-H activation, bidentate direction, Cu-catalyzed, nitration

Cite this article

Wang Yunlong, Zhang Linbao, Niu Junlong, Song Maoping. Copper-Promoted Direct Nitration of Arenes Assisted by an N,O-Bidentate Directing System[J]. Chin. J. Org. Chem., 2019, 39(6): 1761-1766.

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N,O-双齿螯合作用下铜促进的C-H键直接硝基化反应

Copper-Promoted Direct Nitration of Arenes Assisted by an N,O-Bidentate Directing System

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