Chinese Journal of Organic Chemistry ›› 2024, Vol. 44 ›› Issue (3): 1005-1012.DOI: 10.6023/cjoc202309019 Previous Articles     Next Articles

ARTICLES

烯丙基芳香化合物的电化学选择性氧化酯化

李梦帆, 程旭*()   

  1. 南京大学化学化工学院 南京 210023
  • 收稿日期:2023-09-19 修回日期:2023-11-29 发布日期:2024-04-02
  • 基金资助:
    国家自然科学基金(22071105); 国家自然科学基金(22031008)

Chemoselective Electro-oxidation of Allyl Arene to Ester

Mengfan Li, Xu Cheng()   

  1. School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023
  • Received:2023-09-19 Revised:2023-11-29 Published:2024-04-02
  • Contact: *E-mail: chengxu@nju.edu.cn
  • Supported by:
    National Natural Science Foundation of China(22071105); National Natural Science Foundation of China(22031008)

An electrochemical C—H and C—C bond esterification reaction with allyl arene as a substrate is reported. This oxidation takes place selectively at the benzylallyl C—H site instead of other benzylic C—H groups. Since the reaction does not require acid/base catalysis for esterification, tertiary alcohol is suitable for the synthesis of the corresponding ester. In addition, side reactions such as transesterification can be avoided with this neutral protocol.

Key words: allyl, benzyl, electrochemistry, esterification