Chinese Journal of Organic Chemistry ›› 2024, Vol. 44 ›› Issue (4): 1094-1105.DOI: 10.6023/cjoc202311006 Previous Articles     Next Articles

REVIEWS

硝基化合物均相催化氢化研究进展

侯梦莹, 王爱娥*(), 黄培强*()   

  1. 厦门大学化学化工学院化学系 福建省化学生物学重点实验室 福建厦门 361005
  • 收稿日期:2023-11-05 修回日期:2023-12-01 发布日期:2023-12-15
  • 基金资助:
    福建省自然科学基金(2019J01018)

Recent Progress in Homogeneous Catalytic Hydrogenation of Nitro Compounds

Mengying Hou, Ai'e Wang(), Peiqiang Huang()   

  1. Fujian Provincial Key Laboratory of Chemical Biology, Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, Fujian 361005
  • Received:2023-11-05 Revised:2023-12-01 Published:2023-12-15
  • Contact: E-mail: aiewang@xmu.edu.cn;pghuang@xmu.edu.cn
  • Supported by:
    Natural Science Foundation of Fujian Province(2019J01018)

Amines, particularly primary amines, are a class of important compounds, which are frequently used in the synthesis of pharmaceuticals, agrochemicals, dyes as well as a variety of fine and specialty chemicals. The reduction of nitro compounds is an indispensable route for the production of primary amines, especially aniline and its derivatives. In this context, the catalytic hydrogenation represents the most efficient, atomic economical and environmentally friendly method. In general, the reaction mainly relies on heterogeneous catalysts. And most of the recent reports focus on the development and modification of heterogeneous catalysts. Homogeneous catalysts for the hydrogenation of nitro compounds are scarcely explored. Given the structure of homogeneous metal catalysts can be readily modified and adjusted by the application of different central metal and ligand to regulate the catalytic process, the high efficient and selective reduction can be realized by choosing the appropriate combination of metals and ligands. The development and recent progress of homogeneous catalytic hydrogenation of nitro compounds are systematically summarized, the challenges faced in this field are discussed and a perspective on this topic is made.

Key words: homogeneous catalysis, hydrogenation, nitro compound, amine, chemoselectivity