Synthesis and Bioactivity of Three-Ring Heterocyclic Schiff Base Derivatives

doi:10.6023/cjoc1112241

Chin. J. Org. Chem. ›› 2012, Vol. 32 ›› Issue (08): 1473-1478.DOI: 10.6023/cjoc1112241 Previous Articles Next Articles

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含三元杂环席夫碱类衍生物的合成及生物活性研究

熊壮, 李海畅, 梁娜, 尹娟, 卢平, 薛伟

贵州大学精细化工研究开发中心教育部绿色农药与农业生物工程重点实验室贵阳 550025

收稿日期:2011-12-24 修回日期:2012-02-26 发布日期:2012-04-11
通讯作者: 薛伟 E-mail:wxue@gzu.edu.cn
基金资助:
国家自然科学基金(No. 21062005)和贵州大学研究生创新基金(No. 2011033)资助项目

Synthesis and Bioactivity of Three-Ring Heterocyclic Schiff Base Derivatives

Xiong Zhuang, Li Haichang, Liang Na, Yin Juan, Lu Ping, Xue Wei

Key Laboratory of Green Pesticide and Bioengineering, Ministry of Education, Research and Development Center for Fine Chemicals, Guizhou University, Guiyang 550025

Received:2011-12-24 Revised:2012-02-26 Published:2012-04-11
Supported by:
Project supported by the National Natural Science Foundation of China (No. 21062005), and the Innovation Foundation for Postgraduate Students in Guizhou University (No. 2011033).

Ten novel three-ring heterocyclic Schiff-base derivatives were designed and synthesized. Their structures of all these compounds were confirmed by ¹H NMR, ¹³C NMR, IR spectra and elemental analysis. The preliminary result of bioassay showed that the title compounds exhibited some degree of antifungal activities on G. zeae, C. mandshurica and F. oxysporum under 50 mg/L concentration.

Key words: triazole, pyridazinone, bioactivity, synthesis

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Xiong Zhuang, Li Haichang, Liang Na, Yin Juan, Lu Ping, Xue Wei. Synthesis and Bioactivity of Three-Ring Heterocyclic Schiff Base Derivatives[J]. Chin. J. Org. Chem., 2012, 32(08): 1473-1478.

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含三元杂环席夫碱类衍生物的合成及生物活性研究

Synthesis and Bioactivity of Three-Ring Heterocyclic Schiff Base Derivatives

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