有机化学 ›› 2017, Vol. 37 ›› Issue (9): 2442-2448.DOI: 10.6023/cjoc201702035 上一篇    下一篇

研究简报

阴、阳离子型水溶性卟啉的有效合成

常毅, 刘梦阳, 牛梦园   

  1. 河南师范大学化学化工学院 新乡 453007
  • 收稿日期:2017-02-25 修回日期:2017-04-12 出版日期:2017-09-25 发布日期:2017-05-02
  • 通讯作者: 常毅 E-mail:yc0906@htu.edu.cn
  • 基金资助:

    河南省高等学校重点科研项目计划(No.16A150012)、河南师范大学青年科学基金(No.214QK15)、河南师范大学博士科研启动基金(No.qd15113)资助项目.

Efficient Synthesis of Anionic and Cationic Water-Soluble Porphyrins

Chang Yi, Liu Mengyang, Niu Mengyuan   

  1. School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang 453007
  • Received:2017-02-25 Revised:2017-04-12 Online:2017-09-25 Published:2017-05-02
  • Contact: 10.6023/cjoc201702035 E-mail:yc0906@htu.edu.cn
  • Supported by:

    Project supported by the Key Program for High School of Henan Province (No. 16A150012) and the Science Foundation for Young Scholar of Henan Normal University (No. 214QK15) and the Doctoral Science Research Foundation of Henan Normal University (No. qd15113).

meso-四(4-吡啶基)卟啉和meso-四(4-羟基苯基)卟啉为原料,三乙二醇单甲醚单元取代和锰离子配位作为功能性修饰手段,按照优化的反应条件,高效合成了吡啶基阳离子型和磺酸基阴离子型水溶性卟啉化合物.该类方法操作简单、收率高、反应条件温和,为同类型水溶性卟啉的合成提供了很好的合成方法.

关键词: 水溶性, 卟啉, 锰卟啉, 取代基团, 合成, 修饰

A kind of cationic water-soluble porphyrin containing pyridinium group and a kind of anionic water-soluble porphyrin containing sulfonic group were synthesized efficiently according to the chosen conditions. During the synthesis process, 5,10,15,20-tetra(pyridin-4-yl)porphyrin and 5,10,15,20-tetra-phenol porphyrin were chosen as the precursors, while triethylene glycol monomethyl ether and manganese were introduced on porphyrin as the functional group. These procedures have the advantages of operation simplicity, high yields, mild conditions, and provide a good method for the synthesis of similar types of water soluble porphyrins at the same time.

Key words: water-soluble, porphyrins, manganese porphyrin, substituents, synthesis, modification