有机化学 ›› 2020, Vol. 40 ›› Issue (10): 3426-3430.DOI: 10.6023/cjoc202005022 上一篇    下一篇

研究论文

芳基硼酸和氟仿衍生三氟甲基银的氧化偶联反应

欧阳瑶, 徐修华, 卿凤翎   

  1. 中国科学院上海有机化学研究所 分子合成卓越中心 有机氟化学重点实验室 上海 200032
  • 收稿日期:2020-05-09 修回日期:2020-06-03 发布日期:2020-06-10
  • 通讯作者: 卿凤翎 E-mail:flq@mail.sioc.ac.cn
  • 基金资助:
    国家自然科学基金(Nos.21421002,21991211)和中国科学院战略先导研究计划(No.XDB20000000)资助项目.

Oxidative Coupling Reactions of Arylboronic Acids and Fluoroform-Derived AgCF3

Ouyang Yao, Xu Xiuhua, Qing Fengling   

  1. Key Laboratory of Organofluorine Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032
  • Received:2020-05-09 Revised:2020-06-03 Published:2020-06-10
  • Supported by:
    Project supported by the National Natural Science Foundation of China (Nos. 21421002, 21991211) and the Strategic Priority Research Program of the Chinese Academy of Sciences (No. XDB20000000).

以K2S2O8为氧化剂,芳基硼酸与氟仿衍生的AgCF3发生氧化偶联反应生成三氟甲基取代的芳烃及杂芳烃.该反应为构建Caryl—CF3键提供了新方法.

关键词: 氧化三氟甲基化反应, 硼酸, 氟仿, 三氟甲基银

A silver-mediated oxidative coupling reaction of arylboronic acids with fluoroform-derived AgCF3 using K2S2O8 as oxidant was developed. This reaction provides a new route to trifluoromethylated arenes.

Key words: oxidative trifluoromethylation, arylboronic acids, fluoroform, trifluoromethyl silver