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有机化学
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有机化学 ›› 2005, Vol. 25 ›› Issue (07): 788-799. 上一篇    下一篇

综述与进展

海洋溴吡咯生物碱的研究进展

刘家峰，郭松坡，姜标*   

  1. (中国科学院上海有机化学研究所金属有机化学国家重点实验室 上海 200032)
  • 收稿日期:2004-12-28 修回日期:2005-04-21 发布日期:2005-06-30
  • 通讯作者: 姜标

Progress in the Study of Marine Bromopyrrole Alkaloids

LIU Jia-Feng,GUO Song-Po,JIANG Biao*   

  1. (State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry,
    Chinese Academy of Sciences, Shanghai 200032)
  • Received:2004-12-28 Revised:2005-04-21 Published:2005-06-30
  • Contact: JIANG Biao

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1813

被引次数

68

大量的溴吡咯生物碱从海绵中得到分离, 并表现出良好的生理活性. 这类化合物因其结构的新颖性、多样性、以及良好的生理活性而成为合成化学家关注的焦点. 综述了近年来海洋溴吡咯生物碱的分离和合成进展.

关键词: 生物碱, 合成, 溴吡咯, 分离, 海洋天然产物

A lot of bromopyrrole alkaloids have been isolated from marine sponges, and exhibited good or excellent biological activities. The class of compounds has stimulated a great deal of interest on synthetic chemists due to their structural novelty, molecular diversity, and promising biological activities. In this article the recent progress in the isolation and synthesis of marine bromopyrrole alkaloids has been reviewed.

Key words: alkaloid, marine natural product, synthesis, isolation, bromopyrrole