Chin. J. Org. Chem. ›› 2012, Vol. 32 ›› Issue (10): 1827-1835.DOI: 10.6023/cjoc1202071 Previous Articles     Next Articles



刘帅, 彭家建, 厉嘉云, 白赢, 肖文军, 来国桥   

  1. 杭州师范大学有机硅化学及材料技术教育部重点实验室 杭州 310012
  • 收稿日期:2012-02-07 修回日期:2012-04-11 发布日期:2012-05-21
  • 通讯作者: 彭家建, 来国桥;
  • 基金资助:

    浙江省重点科技创新团队专项(No. 2009R50016)、浙江省自然科学基金(No. Y4100248)资助项目.

Progress in Asymmetric Hydrosilylation of Ketones by Non-precious Metal Catalyst

Liu Shuai, Peng Jiajian, Li Jiayun, Bai Ying, Xiao Wenjun, Lai Guoqiao   

  1. Key Laboratory of Organosilicon Chemistry and Material Technology, Ministry of Education, Hangzhou Normal University, Hangzhou 310012
  • Received:2012-02-07 Revised:2012-04-11 Published:2012-05-21
  • Supported by:

    Project supported by the Aid Program for Key Science and Technology Innovative Research Team in Zhejiang Province (No. 2009R50016) and the Natural Science Fundation of Zhejiang Province (No. Y4100248).

As important intermediates for the development of biologically active molecules and fragrance etc., chiral secondary alcohols are synthesized through asymmetric hydrogenation. Recently, the asymmetric hydrosilylation process has been attracted because of its mild reaction conditions as well as inexpensive and safer reagent system. In this paper, some information about the recent development of the catalysts of the non-precious metal (Zn, Cu and so on) for asymmetric hydrosilylation reaction of prochiral ketones is briefly reviewed.

Key words: asymmetric hydrosilylation, non-precious metal catalyst, chiral alcohol, prochiral ketone, progress