Chin. J. Org. Chem. ›› 2013, Vol. 33 ›› Issue (01): 174-177.DOI: 10.6023/cjoc201208039 Previous Articles     Next Articles



杨留攀, 李加荣, 柴洪新, 袁洪, 张奇, 史大昕   

  1. 北京理工大学化工与环境学院 北京 100081
  • 收稿日期:2012-08-31 修回日期:2012-09-19 发布日期:2012-09-26
  • 通讯作者: 史大昕
  • 基金资助:

    北京理工大学研究生科技创新专项计划(No. 2011CX0436)资助项目.

Synthesis of 2,3,8,9-Tetrahydropyrido[2,3-d:6,5-d']dipyrimidine-4,6-diones

Yang Liupan, Li Jiarong, Chai Hongxin, Yuan Hong, Zhang Qi, Shi Daxin   

  1. School of Chemical Engineering and Environment, Beijing Institute of Technology, Beijing 100081
  • Received:2012-08-31 Revised:2012-09-19 Published:2012-09-26
  • Supported by:

    Project supported by the Science and Technology Innovation Program of Beijing Institute of Technology (No. 2011CX0436).

2,3,8,9-Tetrahydropyrido[2,3-d:6,5-d']dipyrimidine-4,6-diones were synthesized by using malononitrile, ortho-triethyl and pyridine as starting materials in three steps reaction including cyclization, ammonolysis and reaction with ketones under the catalysis of sodium methoxide. The structures of the products were confirmed by NMR, IR, ESI and elemental analysis.

Key words: pyridodipyrimidinediones, heterocycle, synthesis