Chin. J. Org. Chem. ›› 2013, Vol. 33 ›› Issue (06): 1195-1234.DOI: 10.6023/cjoc201304039 Previous Articles     Next Articles

Reviews

2010~2013之海洋微生物新天然产物

赵成英, 朱统汉, 朱伟明   

  1. 海洋药物教育部重点实验室 中国海洋大学医药学院 青岛 266003
  • 收稿日期:2013-04-24 修回日期:2013-05-22 出版日期:2013-06-25 发布日期:2013-05-24
  • 通讯作者: 朱伟明 E-mail:weimingzhu@ouc.edu.cn
  • 基金资助:

    国家高科技发展计划(Nos.2013AA092901, 2012AA09210);国家自然科学基金(No.21172204)和重点基础研究发展计划(No.2010CB833804)资助项目

New Marine Natural Products of Microbial Origin from 2010 to 2013

Zhao Chengying, Zhu Tonghan, Zhu Weiming   

  1. Key Laboratory of Marine Drugs, Educational Minister of China, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003
  • Received:2013-04-24 Revised:2013-05-22 Online:2013-06-25 Published:2013-05-24
  • Supported by:

    Project supported by the National High-tech R&D Program of China (Nos.2013AA092901, 2012AA092104), the National Natural Science Fundation of China (No.21172204), and the National Basic Research Program of China (No.2010CB833804)

The microbial drug research started from the 20th century has become the foundation of modern drugs.Nowadays, almost 10% of all presently known compounds with bioactivities are of microbial origin.In the past decade, natural products from marine microorganisms that were regarded as a very potential resource for the drug discovery have gained great attention.This paper introduces the sources, structures and bioactivities of 895 new compounds from marine bacteria, actinomycetes and fungi reported between January 2010 and February 2013.

Key words: marine natural products, cytotoxicity, marine microbes, bacteria, actinomycetes, fungi