Chin. J. Org. Chem. ›› 2013, Vol. 33 ›› Issue (10): 2232-2236.DOI: 10.6023/cjoc201304040 Previous Articles     Next Articles

Notes

磺酸功能化的聚乙二醇6000催化下合成二氢吡咯酮类化合物

田拴宝, 郝永兵   

  1. 新乡医学院基础医学院 新乡 453003
  • 收稿日期:2013-04-24 修回日期:2013-06-07 出版日期:2013-10-25 发布日期:2013-06-21
  • 通讯作者: 田拴宝 E-mail:tianshuanbao2006@163.com

Sulfuric Acid-Modified Polyethylene Glycol 6000 Catalyzed Synthesis of Dihydropyrrolone

Tian Shuanbao, Hao Yongbing   

  1. School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang 453003
  • Received:2013-04-24 Revised:2013-06-07 Online:2013-10-25 Published:2013-06-21

A series of dihydropyrrolones were synthesized in high yields by reaction of two same/different primary amines, but-2-ynedioates and formaldehyde in the presence of sulfuric acid-modified polyethylene glycol 6000 in MeOH at room temperature. All products were characterized by 1H NMR, 13C NMR, IR and elemental analysis.

Key words: dihydropyrrolones, sulfuric acid-modified polyethylene glycol 6000, but-2-ynedioates, multi-component reaction, synthesis