Chin. J. Org. Chem. ›› 2014, Vol. 34 ›› Issue (4): 706-716.DOI: 10.6023/cjoc201310015 Previous Articles     Next Articles



宋沙沙, 周宏勇, 李小娜, 王丽华, 李云庆, 王家喜   

  1. 河北工业大学化工学院 天津 300130
  • 收稿日期:2013-10-14 修回日期:2013-12-05 发布日期:2013-12-13
  • 通讯作者: 王家喜
  • 基金资助:

    河北省自然科学基金(No. B2011202087)资助项目

Advance of Glucosamine and Their Derivatives as Chiral Ligands in Asymmetric Syntheses

Song Shasha, Zhou Hongyong, Li Xiaona, Wang Lihua, Li Yunqing, Wang Jiaxi   

  1. School of Chemical Engineering, Hebei University of Technology, Tianjin 300130
  • Received:2013-10-14 Revised:2013-12-05 Published:2013-12-13
  • Supported by:

    Project supported by the Natural Science Foundation of Hebei Province (No. B2011202087)

Glucosamine is a chiral compound degraded from widely existed natural product chitosan. It is becoming an ideal raw material for preparation chiral amine, amine/phosphine ligands due to its more chiral centers and strong coordination ability. The application of glucosamine derivatives as chiral ligands in asymmetric organic reactions has become a very active research area. In this paper, the application of glucosamine derivatives in asymmetric allylic alkylation, Heck reaction, 1,4-conjugate addition reaction, epoxidation reaction of olefins and cyclopropanation of olefin has been reviewed.

Key words: chiral ligand, glucosamine, metal complex, asymmetric synthesis