Chin. J. Org. Chem. ›› 2014, Vol. 34 ›› Issue (5): 962-967.DOI: 10.6023/cjoc201310018 Previous Articles     Next Articles



马丽芳, 吕文贤, 黄丹凤, 牛腾, 苏瀛鹏, 王克虎, 胡雨来   

  1. 西北师范大学化学化工学院 兰州 730070
  • 收稿日期:2013-10-15 修回日期:2013-12-10 发布日期:2014-01-15
  • 通讯作者: 黄丹凤;
  • 基金资助:

    国家自然科学基金(No. 21062016)资助项目.

A New Method for the Synthesis of Phenanthridine Compounds

Ma Lifang, L? Wenxian, Huang Danfeng, Niu Teng, Su Yingpeng, Wang Kehu, Hu Yulai   

  1. College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 730070
  • Received:2013-10-15 Revised:2013-12-10 Published:2014-01-15
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 21062016).

5-Methoxyphenanthridin-6(5H)-ones reacted with aryl Grignard reagents to afford phenanthridine compounds. The method has the advantages of mild reaction conditions with good yields and provides a new synthetic procedure for the phenanthridine derivatives. However, the products were phenanthridin-6(5H)-ones when alkyl magnesium bromide reacted with 5-methoxyphenanthridin-6(5H)-ones.

Key words: phenanthridines, 5-methoxyphenanthridin-6(5H)-ones, Weinreb amides, Grignard reagents, synthesis