Chin. J. Org. Chem. ›› 2015, Vol. 35 ›› Issue (5): 984-996.DOI: 10.6023/cjoc201409029 Previous Articles     Next Articles

REVIEW

Pd催化(杂环)芳基羧酸脱羧的偶联反应研究进展

付拯江, 李兆杰, 熊起恒, 蔡琥   

  1. 南昌大学化学学院 南昌 330031
  • 收稿日期:2014-09-18 修回日期:2014-11-13 出版日期:2015-05-25 发布日期:2014-12-18
  • 通讯作者: 蔡琥 E-mail:caihu@ncu.edu.cn
  • 基金资助:

    国家重点基础研究发展规划(No.2012CBA01204)、国家自然科学基金(Nos.21301088,21162015)、江西省自然科学基金(No.20142BAB213001)资助项目.

Recent Progress in Pd-Catalyzed Decarboxylative Coupling Reactions of (Hetero)aromatic Carboxylic Acids

Fu Zhengjiang, Li Zhaojie, Xiong Qiheng, Cai Hu   

  1. College of Chemistry, Nanchang University, Nanchang 330031
  • Received:2014-09-18 Revised:2014-11-13 Online:2015-05-25 Published:2014-12-18
  • Supported by:

    Project supported by the National Basic Research Program of China (No.2012CBA01204), the National Natural Science Foundation of China (Nos.21301088, 21162015), and the Natural Science Foundation of Jiangxi Province (No.20142BAB213001).

Since carboxylic acids have distinguishing features of non-toxicity, low cost, ready availability and easy storage, Pd-catalyzed decarboxylative coupling reactions of (hetero)aromatic carboxylic acids have been obtained rapid development since this century, and have exhibited a tendency toward replacement of traditional coupling reactions. The coupling reactions of Pd-catalyzed decarboxylation of aromatic carboxylic acids with various substrates of olefins, aryl halides, arenes, aryltrifluoroborates and etc. are reviewed, and the relevant reaction mechanisms are discussed.

Key words: Pd, (hetero)aromatic carboxylic acid, decarboxylation, coupling reaction