Chin. J. Org. Chem. ›› 2015, Vol. 35 ›› Issue (7): 1407-1413.DOI: 10.6023/cjoc201412044 Previous Articles     Next Articles



卢勇平, 祁伟鹏, 翁国栋, 张兴贤   

  1. 浙江工业大学药学院 浙江杭州 310032
  • 收稿日期:2014-12-27 修回日期:2015-03-11 发布日期:2015-03-24
  • 通讯作者: 张兴贤
  • 基金资助:

    国家自然科学基金(Nos. 21372203, 21272076)资助项目.

Progresses in Total Synthesis of Guaiane Sesquiterpenes and Their Analogues

Lu Yongping, Qi Weipeng, Weng Guodong, Zhang Xingxian   

  1. College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou, Zhejiang 310032
  • Received:2014-12-27 Revised:2015-03-11 Published:2015-03-24
  • Supported by:

    Project supported by the National Natural Science Foundation of China (Nos. 21372203, 21272076).

The recent progresses in the total synthesis of guaiane sesquiterpenes and their analogues are reviewed, which include the carbene cyclization-cycloaddition cascade reaction, olefin ring closing metathesis reaction, intramolecular aldol reaction as the key steps to construct basic ring system of these natural products.

Key words: guaiane sesquiterpenes, natural products, total synthesis