Chin. J. Org. Chem. ›› 2017, Vol. 37 ›› Issue (10): 2717-2724.DOI: 10.6023/cjoc201704039 Previous Articles     Next Articles



徐海珍a, 谢丽芬b, 韩廷锋b, 何敬立b, 朱有全b   

  1. a 天津师范大学化学学院 天津 300387;
    b 南开大学化学学院 元素有机化学国家重点实验室 天津 300071
  • 收稿日期:2017-04-24 修回日期:2017-05-10 发布日期:2017-06-07
  • 通讯作者: 徐海珍, 朱有全;
  • 基金资助:


Synthesis,Herbicidal Activities of Novel Triketone Compounds Containing 4-Substituted Cyclopentane-1,3-dione Moiety

Xu Haizhena, Xie Lifenb, Han Tingfengb, He Jinglib, Zhu Youquanb   

  1. a College of Chemistry, Tianjin Normal University, Tianjin 300387;
    b State Key Laboratory of Elemento-organic Chemistry, College of Chemistry, Nankai University, Tianjin 300071
  • Received:2017-04-24 Revised:2017-05-10 Published:2017-06-07
  • Contact: 10.6023/cjoc201704039;
  • Supported by:

    Project supported by the National Natural Science Foundation of China (Nos.21072108,21372134).

To find new lead compounds with muti-bioactivities, a series of novel triketone derivatives containing 4-substituted cyclopentane-1,3-dione were designed on the base of various commercial products. The target compounds were synthesized from cyclopentane-1,3-dione in six steps. Their structures were confirmed by IR, 1H NMR spectra and HRMS. The preliminary greenhouse bioassay results indicated that some compounds showed obvious inhibition effects against Brassica campestris, and the inhibition rate was more than 80% at 100 μg/mL. In the pre-and post-emergence, some of them exhibited excellent herbicidal activities against Brassica campestris, and the herbicidal activity was more than 90% at 1500 g/ha.

Key words: triketone, 4-substituted cyclopentane-1,3-dione, synthesis, herbicidal activity