Chin. J. Org. Chem. ›› 2018, Vol. 38 ›› Issue (1): 40-50.DOI: 10.6023/cjoc201708006 Previous Articles     Next Articles

Special Issue: 庆祝吴养洁院士九十华诞专辑



刘强a, 王彬a, 彭小水a,b, 黄乃正a,b   

  1. a 香港中文大学化学系及合成化学国家重点实验室 香港;
    b 香港中文大学深圳研究院 深圳市药用有机小分子化学合成重点实验室 深圳 518507
  • 收稿日期:2017-08-04 修回日期:2017-09-08 发布日期:2017-09-15
  • 通讯作者: 黄乃正
  • 基金资助:


Effects of Additives in Iron-Catalyzed Cross-Coupling Reactions Involving Grignard Reagents

Liu Qianga, Wang Bina, Peng Xiaoshuia,b, Wong Henry N. C.a,b   

  1. a Department of Chemistry, The Chinese University of Hong Kong, and State Key Laboratory of Synthetic Chemistry, Hong Kong;
    b Shenzhen Municipal Key Laboratory of Chemical Synthesis of Medicinal Organic Molecules, Shenzhen Research Institute, The Chinese University of Hong Kong, Shenzhen 518507
  • Received:2017-08-04 Revised:2017-09-08 Published:2017-09-15
  • Contact: 10.6023/cjoc201708006
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 21672181/21272199), the Shenzhen Science and Technology Innovation Committee (No. JCYJ20160608151520697), the National Natural Science Foundation of China and the Research Grants Council of Hong Kong, SAR (RGC) Joint Research Scheme (No. N_CUHK451/13), the RGC (Nos. 403012/CUHK14309216/CUHK14303815, PolyU C5023-14G), and the State Key Laboratory of Synthetic Chemistry and GHP/004/16GD from Innovation and Technology Commission.

Iron-catalyzed cross-coupling reactions between organometallic nucleophiles and organic halides as electrophiles represent one of the most powerful methods in the field of carbon-carbon bond construction. This review is concerned with the additive effect in iron-catalyzed cross-coupling reactions of Grignard reagents, whose results were published in recent years.

Key words: iron-catalyzed, cross-coupling, Grignard reagents, additive effect