Chin. J. Org. Chem. ›› 2018, Vol. 38 ›› Issue (3): 541-554.DOI: 10.6023/cjoc201710028 Previous Articles     Next Articles

Special Issue: 有机超分子化学合辑



房蕾a,b, 林伟彬a,b, 沈赟a, 陈传峰a,b   

  1. a 中国科学院化学研究所 分子识别与功能院重点实验室 北京 100190;
    b 中国科学院大学 北京 100049
  • 收稿日期:2017-10-24 修回日期:2017-11-16 发布日期:2017-11-28
  • 通讯作者: 陈传峰,
  • 基金资助:


Applications of Helicenes and Their Derivatives in Asymmetric Catalysis

Fang Leia,b, Lin Weibina,b, Shen Yuna, Chen Chuanfenga,b   

  1. a Key Laboratory of Molecular Recognition and Functions, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190;
    b University of Chinese Academy of Sciences, Beijing 100049
  • Received:2017-10-24 Revised:2017-11-16 Published:2017-11-28
  • Contact: 10.6023/cjoc201710028
  • Supported by:

    Project supported by the National Natural Science Foundation of China (Nos. 21572233, 51373180), and the Strategic Priority Research Program of Chinese Academy of Sciences (No. XDB12010400).

Helicenes are a kind of π-conjugated helical compounds which are consisted of ortho-fused benzene or other aromatic rings. Compared to other kinds of chiral catalysts, studies on helicene-based catalysts with helical chirality showed late start and lagging development. However, since helicene molecules exhibit structural rigidity, thermal stability, easily functionalization, and excellent chiral environment for asymmetric catalysis by continuous elaborate curve in three-dimensional space, investigation on the synthesis of helicene-based chiral catalysts and their applications in asymmetric catalysis have attracted increasing interest in recent years. According to the different roles of the helicenes played in the asymmetric catalysis, the helicene-based catalysts can be classified into chiral inducers, helically chiral ligands and helical organocatalysts, and their applications in asymmetric catalysis will be focused on in this review, respectively.

Key words: helicene, asymmetric catalysis, chiral induction, helical ligand, organocatalyst