Chinese Journal of Organic Chemistry ›› 2020, Vol. 40 ›› Issue (1): 15-27.DOI: 10.6023/cjoc201906007 Previous Articles     Next Articles


王少华a,b,c, 张帮红c, 陈洁a,b, 郑莹莹a,b, 冯娜a,b, 马爱军a,b, 徐学涛a,b, Abdullah M. Asirid   

  1. a 五邑大学生物科技与大健康学院 广东江门 529020;
    b 江门市大健康国际创新研究院 广东江门 529020;
    c 兰州大学药学院 兰州 730000;
    d Faculty of Science, King Abdulaziz University, Jeddah 999088
  • 收稿日期:2019-06-06 修回日期:2019-09-01 发布日期:2019-09-05
  • 通讯作者: 马爱军, 徐学涛;
  • 基金资助:

Recent Progress in Synthesis of Polysubstituted Pyrazoles

Wang Shaohuaa,b,c, Zhang Banghongc, Chen Jiea,b, Zheng Yingyinga,b, Feng Naa,b, Ma Aijuna,b, Xu Xuetaoa,b, Abdullah M. Asirid   

  1. a School of Biotechnology and Health Sciences, Wuyi University, Jiangmen, Guangdong 529020;
    b International Healthcare Innovation Institute, Jiangmen, Guangdong 529000;
    c School of Pharmacy, Lanzhou University, Lanzhou 730000;
    d Faculty of Science, King Abdulaziz University, Jeddah 999088
  • Received:2019-06-06 Revised:2019-09-01 Published:2019-09-05
  • Supported by:
    Project supported by the the National Natural Science Foundation of China (Nos. 21472077, 21772071), the Department of Education of Guangdong Province (Nos. 2017KTSCX185, 2017KSYS010, 2016KCXTD005), and the High-level Talent Research Start-up Project of Wuyi University (Nos. 2018AL002, 2018AL003).

Pyrazole, an important class of nitrogen-containing five-member hetrocyclic compounds, widely exists in natural products, bio-active molecules and drugs, and it is also a valuable intermediate in organic synthesis. The synthesis of polysubstituted pyrazoles has attracted much attention and developed rapidly in recent years. Herein, the recent research progress in the construction of polysubstituted pyrazoles is summarized.

Key words: pyrazole, synthesis, research process