Chinese Journal of Organic Chemistry ›› 2020, Vol. 40 ›› Issue (8): 2394-2401.DOI: 10.6023/cjoc202004019 Previous Articles     Next Articles

铑催化的丙酮肟醚导向的苯酚的邻位烯基化反应

刘玲玲, 杨闪, 韩昳, 戴晨阳, 史达清, 黄志斌, 赵应声   

  1. 苏州大学材料与化学化工学部 苏州 215123
  • 收稿日期:2020-04-13 修回日期:2020-05-22 出版日期:2020-08-25 发布日期:2020-06-01
  • 通讯作者: 黄志斌, 赵应声 E-mail:zbhuang@suda.edu.cn;yszhao@suda.edu.cn
  • 基金资助:
    国家自然科学基金(Nos.21772139,21572149)、江苏省高等学校自然科学基金重大基础研究(Nos.15KJA150006,17KJA150006)、江苏省杰出青年自然科学基金(No.BK2018g0041)、苏州科技基础设施(No.SZS2018201708)和江苏高校优势学科建设工程资助项目.

Rhodium-Catalyzed ortho-Alkenylation of Phenols Directed by Acetone Oxime Ether

Liu Lingling, Yang Shan, Han Yi, Dai Chenyang, Shi Daqing, Huang Zhibin, Zhao Yingsheng   

  1. College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123
  • Received:2020-04-13 Revised:2020-05-22 Online:2020-08-25 Published:2020-06-01
  • Supported by:
    Project supported by the National Natural Science Foundation of China (Nos. 21772139, 21572149), the Major Basic Research Project of the Natural Science Foundation of Jiangsu Higher Education Institutions (Nos. 15KJA150006, 17KJA150006), the Jiangsu Province Natural Science Found for Distinguished Young Scholars (No. BK2018g0041), the Project of Scientific and Technologic Infrasracture of Suzhou (No. SZS2018201708) and the Priority Academic Program Development of Jiangsu Higher Education Institutions Project.

A practical rhodium-catalyzed highly regioselective ortho-alkenylation of phenolic compound under the assistance of weak coordination center acetoxime ether was developed. This strategy has advantages of simple and mild reaction conditions, wide scope of substrate and high regioselectivity. This protocol provids an efficient and new method for the regioselective ortho-alkenylation of phenols.

Key words: phenol, acetone oxime ether, alkenylation