Chinese Journal of Organic Chemistry ›› 2021, Vol. 41 ›› Issue (8): 3089-3096.DOI: 10.6023/cjoc202104030 Previous Articles     Next Articles



李晓颖, 李培贺, 王峥, 付辉, 戴啟谱*()   

  1. 北京理工大学化学与化工学院 原子分子簇科学教育部重点实验室 光电材料北京市重点实验室 北京 100081
  • 收稿日期:2021-04-15 修回日期:2021-05-15 发布日期:2021-06-02
  • 通讯作者: 戴啟谱
  • 基金资助:
    北京理工大学优秀青年学者研究基金(3190012211808); 北京理工大学优秀青年学者研究基金(3190012331518); 北京理工大学优秀青年学者研究基金(3190012331523); 国家自然科学基金(21871026)

Palladium-Catalyzed Intramolecular Decarboxylative Allylic Amination of Aroyloxycarbamates

Xiaoying Li, Peihe Li, Zheng Wang, Hui Fu, Qipu Dai()   

  1. Beijing Key Laboratory of Photoelectronic/Electrophotonic, Key Laboratory of Cluster Science of Ministry of Education, School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing 100081
  • Received:2021-04-15 Revised:2021-05-15 Published:2021-06-02
  • Contact: Qipu Dai
  • Supported by:
    Excellent Young Scholars Research Fund of Beijing Institute of Technology(3190012211808); Excellent Young Scholars Research Fund of Beijing Institute of Technology(3190012331518); Excellent Young Scholars Research Fund of Beijing Institute of Technology(3190012331523); National Natural Science Foundation of China(21871026)

Allylamine compounds are one of the important compounds in organic synthetic chemistry and pharmaceutical chemistry, the synthetic methods of which are concerned. Using aroyloxycarbamates as start material, which was prepared in situ by cheap and easy-available carboxylic acid and hydroxylamine, allylamine compounds were synthesized by decarboxylation in one step. The reaction conditions are mild and the substrate is generally applicable. Moreover, the reaction realized the synthesis of indole.

Key words: palladium-catalysis, aroyloxycarbamate, decarboxylation, allylic amination, allylamine